γδ T Lymphocyte Homeostasis Is Negatively Regulated by β2-Microglobulin
نویسندگان
چکیده
منابع مشابه
Relationship between Hl-a Antigens and Β2-microglobulin as Studied by Immunofluorescence on the Lymphocyte Membrane
The antibody-induced redistribution of beta2-microglobulin (beta2-micro) and HL-A antigens on the surface of living lymphocytes was studied by immunofluorescence. When all beta2-micro was redistributed on the lymphocyte membrane by specific rabbit antibodies and goat antirabbit Ig conjugates, the HL-A antigens were no more detectable with anti-HL-A conjugates outside the beta2-micro caps alread...
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ItL-A antigens prepared from human lymphoid cells by treatment of either intact cells or membranes with papain or nonionic detergents have been shown to contain two polypeptide chains. The antigen prepared by treatment of cells or cell membranes with papain contains polypeptide chains with a mol wt of about 34,000 and 11,000 (1), whereas the detergent-solubilized antigen has polypeptides of too...
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Semaphorins and their receptors play crucial roles not only in axon guidance during neuronal development but also in the regulation of immune responses. Plexin-A4, a member of the plexin-A subfamily, forms a receptor complex with neuropilins and transduces signals for class III semaphorins in the nervous system. Although plexin-A4 is also expressed in the lymphoid tissues, the involvement of pl...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2009
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.0803165